Affinity Groups
| Logo | Name | Description | Tags | Join |
|---|---|---|---|---|
|
Account and Access Management CI Facilitators | A group for CI and RCD professionals responsible for developing and maintaining the Account and Access Management solutions used at their institutions. Participants are invited to share and discuss… | allocation-managementadministering-hpc | Login to join |
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hpc.social | High Performance Computing and related fields, including Big Data, Research Computing, and related hardware and software optimized for these fields, including research software engineering and… | administering-hpccluster-managementcluster-support +6 more tags | Login to join |
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Open OnDemand | An intuitive, innovative, and interactive interface to remote computing resources.Open OnDemand helps computational researchers and students efficiently utilize remote computing resources by making… | open-ondemandadministering-hpccluster-management +4 more tags | Login to join |
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Knowledge Base Resources
| Title | Category | Tags | Skill Level |
|---|---|---|---|
| Containerized Jupyter Notebooks for HPCs | Learning | cloudcloud-computingopenstack +20 more tags | Intermediate |
| High performance computing 101 | Website | administering-hpc | Beginner |
| Hour of Ci | Learning | arcgisgeographic-information-systemadministering-hpc | Beginner |
Engagements
Recruiting
Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling Active
Atrium Health
- Summary and objectives of the proposed experiments:
- An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
- Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
- Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
- Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: Recruiting
People with Expertise
Chad Julius
South Dakota State University
Programs
Campus Champions, Great Plains
Roles
mentor, research computing facilitator
Expertise
Mike Renfro
Tennessee Technological University
Programs
Campus Champions, CCMNet
Roles
CampusChampionsAdmin, research computing facilitator, ci systems engineer, Affinity Group Leader, CCMNet
Expertise
Chris Reidy
University of Arizona
Programs
Campus Champions, CCMNet
Roles
mentor, research computing facilitator, CCMNet
Expertise
People with Interest
Interests
William Lai
Cornell University
Programs
ACCESS CSSN
Roles
mentor, researcher/educator, research computing facilitator, research software engineer, ci systems engineer, Consultant
Interests
Al Tucker
Columbia University in the City of New York
Programs
Campus Champions
Roles
research computing facilitator
